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PSM · Non-communicable diseases: protective factors for breast cancer
Sample itemA woman asks which reproductive factor is associated with a lower risk of breast cancer. Which should the doctor mention?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Early first full-term pregnancy with prolonged lactation
Early first full-term pregnancy and prolonged breastfeeding reduce lifetime exposure to oestrogen and are protective. Early menarche, late menopause and nulliparity lengthen oestrogen exposure and increase risk. These associations support breastfeeding promotion as part of cancer prevention.
Option by option
A. Late menopause
Late menopause prolongs oestrogen exposure and raises the risk.
B. Nulliparity
Nulliparity is a recognised risk factor for breast cancer.
C. Early first full-term pregnancy with prolonged lactation (correct)
Correct. Early first pregnancy and prolonged lactation lower the risk of breast cancer.
D. Early menarche
Early menarche increases the number of ovulatory cycles and the risk.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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