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Physiology · Nerve and muscle: nerve injury grading
Sample itemAfter a severe traction injury, a nerve shows complete loss of axons and its connective tissue sheaths are intact. Which outcome is most likely if the cause is removed?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Good recovery as regrowing axons follow the intact endoneurial tubes
When the endoneurial tubes remain intact, regenerating axons are guided back to their original targets, so recovery can be good though slow, at roughly a millimetre a day. When the tubes are disrupted, axons may stray and recovery needs surgery.
Option by option
A. Good recovery as regrowing axons follow the intact endoneurial tubes (correct)
Correct. Intact sheaths guide regrowing axons to their targets.
B. Recovery only if scar tissue is excised
Scar excision is needed when sheaths are disrupted, not when they are intact.
C. No recovery because the cell body dies
The cell body usually survives a distal injury and mounts a regenerative response.
D. Immediate recovery within hours
Axonal regrowth is slow and cannot occur within hours.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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