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Physiology · Respiratory system: apneusis after pontine section
Sample itemIn an experimental animal, the brainstem is sectioned between the upper and middle pons and both vagi are cut. What breathing pattern results?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Prolonged inspiratory gasps with brief expirations
The pneumotaxic centre in the upper pons and vagal stretch afferents both help terminate inspiration. When both inputs are removed, the apneustic centre drives sustained inspiration, producing apneusis. The medullary groups still generate a basic rhythm, so breathing does not stop.
Option by option
A. Regular breathing identical to normal
The pattern is clearly abnormal because the off-switch for inspiration is lost.
B. Rapid shallow breathing
Rapid shallow breathing follows vagal stimulation, not its removal.
C. Prolonged inspiratory gasps with brief expirations (correct)
Correct. Without the pneumotaxic and vagal off-switches, inspiration is prolonged.
D. Complete and permanent apnoea
The medullary rhythm generator survives, so breathing continues.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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