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Physiology · Special senses: motion sickness
Sample itemA passenger reading in a ship's cabin becomes nauseated, sweaty and pale as the ship rolls, although the eyes see a still room. Which mechanism best explains the symptoms?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Mismatch between vestibular and visual inputs
Motion sickness arises when vestibular signals of movement conflict with visual and proprioceptive signals, activating pathways to the vomiting centre and autonomic outflow. Anticholinergic and antihistamine drugs act on these vestibular pathways.
Option by option
A. Overactivity of the olfactory pathway to cortex
Smell is not the trigger of motion sickness.
B. Direct damage to the cochlea and hearing loss
The cochlea carries hearing, not motion signals.
C. Raised intracranial pressure from a mass lesion
Raised intracranial pressure causes headache and vomiting but not a pattern tied to motion.
D. Mismatch between vestibular and visual inputs (correct)
Correct. Conflicting vestibular and visual signals trigger nausea and autonomic symptoms.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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