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Physiology · Endocrinology: delayed counter-regulation of hypoglycaemia
Sample itemAfter glucagon and adrenaline have acted in the first minutes of insulin-induced hypoglycaemia, which pair of hormones sustains glucose recovery over the next few hours by promoting gluconeogenesis and reducing peripheral glucose use?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Cortisol and growth hormone
Cortisol and growth hormone are slower counter-regulatory hormones. They raise gluconeogenesis and lipolysis and decrease glucose uptake, supporting recovery when the rapid responses fade.
Option by option
A. Calcitonin and parathyroid hormone
These hormones regulate calcium and do not raise glucose.
B. Aldosterone and vasopressin
These regulate salt and water balance rather than glucose.
C. Cortisol and growth hormone (correct)
Correct. These are the slower counter-regulatory hormones that act over hours.
D. Thyroxine and oxytocin
Thyroxine sets metabolic rate and oxytocin acts on the uterus and breast, so neither is a counter-regulatory hormone.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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