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Anaesthesia · Intravenous agents: midazolam premedication in children
Sample itemWhich route and dose of midazolam is commonly used for premedication of an anxious 4-year-old?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Oral 0.5 mg/kg
Oral midazolam 0.5 mg/kg given 20 to 30 minutes before induction gives reliable anxiolysis and sedation in children. The intravenous induction dose is only 0.1 to 0.3 mg/kg.
Option by option
A. Rectal 20 mg/kg
20 mg/kg is a toxic dose.
B. Intravenous 5 mg/kg
5 mg/kg intravenously would be a massive overdose.
C. Intramuscular 5 mg/kg
5 mg/kg is a toxic overdose.
D. Oral 0.5 mg/kg (correct)
Correct. Oral 0.5 mg/kg is the usual dose.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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