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Anaesthesia · Inhalational agents: isoflurane coronary steal
Sample itemIsoflurane has been linked to coronary steal. What is the mechanism?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Dilation of normal coronary arterioles diverts flow from stenosed vessel territories
A potent arteriolar vasodilator can reduce perfusion pressure and divert blood from areas supplied by fixed stenoses to areas with dilatable vessels. The clinical significance is debated.
Option by option
A. Constriction of normal coronary arteries
Isoflurane dilates, not constricts.
B. Dilation of normal coronary arterioles diverts flow from stenosed vessel territories (correct)
Correct. Differential vasodilation steals flow.
C. Direct myocardial necrosis
Myocardial necrosis is not involved.
D. Thrombosis of stenotic vessels
Thrombosis is not the mechanism.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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