Muscle relaxants: pancuronium: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Muscle relaxants: pancuronium

Sample item

Pancuronium causes tachycardia and a rise in blood pressure because of which action?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Vagal blockade and inhibition of noradrenaline reuptake

Pancuronium blocks cardiac muscarinic receptors and inhibits catecholamine uptake, increasing heart rate. It is long-acting and largely renally excreted.

Option by option

  • A. Vagal blockade and inhibition of noradrenaline reuptake (correct)

    Correct. Vagolytic and sympathomimetic effects increase heart rate.

  • B. Direct beta agonism

    It is not a beta agonist.

  • C. Ganglion stimulation

    Ganglion stimulation is not a feature.

  • D. Histamine release

    Histamine release lowers blood pressure.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is A, Vagal blockade and inhibition of noradrenaline reuptake. Pancuronium blocks cardiac muscarinic receptors and inhibits catecholamine uptake, increasing heart rate.

Why is "Direct beta agonism" not the answer?

It is not a beta agonist.

Why is "Ganglion stimulation" not the answer?

Ganglion stimulation is not a feature.

Why is "Histamine release" not the answer?

Histamine release lowers blood pressure.

What concept does this question test?

It tests Muscle relaxants: pancuronium in Anaesthesia. It is long-acting and largely renally excreted.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Muscle relaxants: pancuronium?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.