Local anaesthetics: ropivacaine: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Local anaesthetics: ropivacaine

Sample item

Why is ropivacaine often preferred to bupivacaine for prolonged epidural infusion?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Less cardiotoxicity and less motor block

Ropivacaine is the pure S-enantiomer, which dissociates faster from cardiac sodium channels, so it has a better safety margin. It also causes less motor block at analgesic concentrations.

Option by option

  • A. Less cardiotoxicity and less motor block (correct)

    Correct. Lower cardiotoxicity and motor block.

  • B. Higher potency

    Its potency is slightly lower than bupivacaine.

  • C. Faster onset

    Onset is similar to bupivacaine.

  • D. Ester structure with rapid metabolism

    It is an amide.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is A, Less cardiotoxicity and less motor block. Ropivacaine is the pure S-enantiomer, which dissociates faster from cardiac sodium channels, so it has a better safety margin.

Why is "Higher potency" not the answer?

Its potency is slightly lower than bupivacaine.

Why is "Faster onset" not the answer?

Onset is similar to bupivacaine.

Why is "Ester structure with rapid metabolism" not the answer?

It is an amide.

What concept does this question test?

It tests Local anaesthetics: ropivacaine in Anaesthesia. It also causes less motor block at analgesic concentrations.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Local anaesthetics: ropivacaine?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.