Complications: anaphylaxis investigation: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Complications: anaphylaxis investigation

Sample item

Which blood test supports the diagnosis of anaphylaxis in the 1 to 2 hours after the event?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Serum mast cell tryptase

Tryptase peaks about 1 hour after mast cell degranulation and remains raised for around 6 hours, and a rise above baseline (1.2 times baseline plus 2 microgram/L) is supportive. Later skin testing identifies the culprit.

Option by option

  • A. Troponin

    Troponin is a cardiac marker.

  • B. Serum mast cell tryptase (correct)

    Correct. Tryptase is the marker.

  • C. D-dimer

    D-dimer is a marker for thrombosis.

  • D. Serum amylase

    Amylase is a pancreatic marker.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is B, Serum mast cell tryptase. Tryptase peaks about 1 hour after mast cell degranulation and remains raised for around 6 hours, and a rise above baseline (1.

Why is "Troponin" not the answer?

Troponin is a cardiac marker.

Why is "D-dimer" not the answer?

D-dimer is a marker for thrombosis.

Why is "Serum amylase" not the answer?

Amylase is a pancreatic marker.

What concept does this question test?

It tests Complications: anaphylaxis investigation in Anaesthesia. 2 times baseline plus 2 microgram/L) is supportive. Later skin testing identifies the culprit.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Complications: anaphylaxis investigation?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.