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Dentistry · Oral cancer: verrucous carcinoma
Sample itemAn elderly man who dips snuff has a slow-growing white, warty exophytic mass in the buccal sulcus. Biopsy shows well-differentiated epithelium with broad pushing margins. What is the typical behaviour?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Locally invasive with rare metastasis
Verrucous carcinoma is a well-differentiated variant linked to smokeless tobacco. It grows locally and rarely metastasises, so wide excision is often curative. Radiotherapy is avoided because of reports of anaplastic transformation.
Option by option
A. Frequent distant metastasis to the lung
Distant spread is very uncommon.
B. Spontaneous regression
It does not regress spontaneously.
C. Locally invasive with rare metastasis (correct)
Correct. Local spread with rare nodal disease is typical.
D. Early widespread nodal metastasis
Early nodal spread is typical of conventional carcinoma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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