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General Surgery · Mesenteric ischaemia: chronic
Sample itemA 62-year-old smoker has postprandial abdominal pain, fear of eating and a 10 kg weight loss. Colonoscopy and gastroscopy are normal. What is the likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Chronic mesenteric ischaemia
Chronic mesenteric ischaemia (intestinal angina) occurs with atherosclerotic stenosis of at least two of the three splanchnic arteries and causes pain 15 to 30 minutes after meals. Sitophobia leads to weight loss. CT angiography confirms it, and revascularisation by stenting or bypass is offered.
Option by option
A. Chronic pancreatitis
Chronic pancreatitis causes pain radiating to the back with steatorrhoea.
B. Crohn disease
Crohn disease would show mucosal changes.
C. Chronic mesenteric ischaemia (correct)
Correct. Postprandial pain with weight loss and vascular risk factors suggests intestinal angina.
D. Peptic ulcer disease
Ulcer disease would show lesions on endoscopy.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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