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General Surgery · Salivary glands: adenoid cystic carcinoma
Sample itemA patient with a parotid tumour has facial weakness. Histology shows cribriform pattern and tumour surrounding nerves. Which feature is typical of this tumour?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Perineural invasion with late distant spread
Adenoid cystic carcinoma shows relentless perineural spread, leading to pain or facial palsy, and late haematogenous metastasis to lung even years after treatment. Wide excision with adjuvant radiotherapy is used. Nodal spread is uncommon.
Option by option
A. Perineural invasion with late distant spread (correct)
Correct. Perineural invasion is the hallmark.
B. Early nodal spread
Nodal metastasis is uncommon.
C. Complete cure by enucleation
Enucleation fails because of perineural spread.
D. Spontaneous regression
The tumour is progressive.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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