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General Surgery · Head and neck: nasopharyngeal carcinoma
Sample itemA 35-year-old has a painless upper neck lymph node, unilateral hearing loss from serous otitis media, and epistaxis. Which virus is linked with the suspected tumour?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Epstein-Barr virus
Nasopharyngeal carcinoma is linked to EBV, especially the non-keratinising type, and arises in the fossa of Rosenmuller. Unilateral serous otitis in an adult should prompt nasopharyngeal examination. Treatment is radiotherapy, with chemotherapy for advanced disease.
Option by option
A. Human papillomavirus type 6
HPV 6 is linked to laryngeal papillomas.
B. Epstein-Barr virus (correct)
Correct. EBV is associated with nasopharyngeal carcinoma.
C. Cytomegalovirus
CMV is not linked to this cancer.
D. Hepatitis B virus
Hepatitis B is linked to hepatocellular carcinoma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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