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General Surgery · Shock: septic shock management
Sample itemA patient with pneumonia has fever, a pulse of 120 per minute and BP of 80/50 mmHg and lactate 4 mmol/L. After the first litre of fluid, which is the first-line vasopressor if hypotension persists?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Norepinephrine
Septic shock management consists of early broad-spectrum antibiotics within one hour, source control, an initial crystalloid bolus of about 30 mL/kg, and vasopressors to keep the mean arterial pressure at 65 mmHg or higher. Norepinephrine is the first-line vasopressor, and vasopressin may be added. Hydrocortisone is considered in refractory shock.
Option by option
A. Norepinephrine (correct)
Correct. Norepinephrine is the vasopressor of choice.
B. Isoprenaline
Isoprenaline is a vasodilating inotrope.
C. Dopamine as first choice
Dopamine is associated with more arrhythmias and is second line.
D. Phenylephrine
Phenylephrine is not preferred in septic shock.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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