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General Surgery · Wound healing: skin graft take
Sample itemIn the first 48 hours after application, how does a split-thickness skin graft survive?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Plasmatic imbibition from the wound bed
A graft survives initially by plasmatic imbibition, absorbing nutrients from the serum of the wound bed, and from about day two to three inosculation and capillary ingrowth establish a blood supply. Haematoma, seroma, infection and shear prevent take. Immobilisation and a well-vascularised bed are required.
Option by option
A. Plasmatic imbibition from the wound bed (correct)
Correct. Imbibition sustains the graft early.
B. Inosculation with recipient vessels
Inosculation begins after about 48 hours.
C. Direct arterial anastomosis
Arteries are not anastomosed.
D. Lymphatic flow only
Lymphatics are not the nutritional route.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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