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Microbiology · Mycology
Sample itemA patient in diabetic ketoacidosis develops facial pain and a black necrotic eschar on the nasal turbinate. Biopsy shows broad, ribbon-like hyphae with right-angle branching. What is the organism?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Mucorales (Rhizopus)
Rhinocerebral mucormycosis occurs in diabetic ketoacidosis and neutropenia. Mucorales have broad pauciseptate hyphae branching at wide angles, and they invade blood vessels causing infarction and black eschars.
Option by option
A. Cryptococcus neoformans
Cryptococcus is an encapsulated yeast that causes meningitis.
B. Candida albicans
Candida forms yeasts and pseudohyphae rather than broad hyphae.
C. Mucorales (Rhizopus) (correct)
Broad ribbon-like hyphae with vascular invasion in ketoacidosis define mucormycosis.
D. Aspergillus fumigatus
Aspergillus has narrow septate hyphae branching at acute angles.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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