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Biochemistry · Vitamins and minerals
Sample itemTryptophan can be converted to niacin in the body. About how many milligrams of dietary tryptophan are equivalent to 1 mg of niacin?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. 60 mg
Sixty milligrams of tryptophan yield about one milligram of niacin, so diets rich in protein protect against pellagra. Maize-based diets are poor in available niacin and tryptophan. The conversion needs vitamin B6, riboflavin and iron.
Option by option
A. 30 mg
30 mg understates the amount of tryptophan needed.
B. 60 mg (correct)
Correct. The accepted conversion ratio is 60 mg tryptophan to 1 mg niacin.
C. 120 mg
120 mg overstates the amount of tryptophan needed.
D. 6 mg
6 mg is ten times too low.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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