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General Surgery · Hepatobiliary and pancreatic surgery: pancreaticoduodenectomy complications
Sample itemFive days after a pancreaticoduodenectomy, a patient has fever and a drain output of amylase-rich fluid, with no peritonitis. Which complication is this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Postoperative pancreatic fistula
A leak from the pancreatic-enteric anastomosis produces amylase-rich fluid in the drain and is a common major complication of pancreaticoduodenectomy. Management is drainage with nutritional support, and re-operation is only for sepsis.
Option by option
A. Delayed gastric emptying
Delayed gastric emptying presents with vomiting and high gastric aspirates.
B. Marginal ulcer
Marginal ulcer is a late complication presenting with pain or bleeding.
C. Postoperative pancreatic fistula (correct)
Correct. Amylase-rich drain fluid indicates a pancreatic fistula.
D. Chyle leak
Chyle is milky and rich in triglyceride, not amylase.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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