Bacteriology: donovanosis: practice question

A Microbiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Microbiology · Bacteriology: donovanosis

Sample item

A man has a painless, beefy-red, easily bleeding genital ulcer with no lymph node suppuration. Smear stained with Giemsa shows intracellular bipolar organisms in macrophages. What are these called?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Donovan bodies

Klebsiella granulomatis causes donovanosis (granuloma inguinale), and safety pin shaped Donovan bodies are seen inside macrophages. Negri bodies are in rabies, Guarnieri in smallpox and Councilman in viral hepatitis and yellow fever.

Option by option

  • A. Guarnieri bodies

    Guarnieri bodies are inclusions in smallpox and vaccinia.

  • B. Councilman bodies

    Councilman bodies are apoptotic hepatocytes.

  • C. Donovan bodies (correct)

    Correct. Donovan bodies are intracellular organisms in donovanosis.

  • D. Negri bodies

    Negri bodies are cytoplasmic inclusions in rabies neurones.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Microbiology questions

Questions about this Microbiology question

What is the answer to this Microbiology question?

The best answer is C, Donovan bodies. Klebsiella granulomatis causes donovanosis (granuloma inguinale), and safety pin shaped Donovan bodies are seen inside macrophages.

Why is "Guarnieri bodies" not the answer?

Guarnieri bodies are inclusions in smallpox and vaccinia.

Why is "Councilman bodies" not the answer?

Councilman bodies are apoptotic hepatocytes.

Why is "Negri bodies" not the answer?

Negri bodies are cytoplasmic inclusions in rabies neurones.

What concept does this question test?

It tests Bacteriology: donovanosis in Microbiology. Negri bodies are in rabies, Guarnieri in smallpox and Councilman in viral hepatitis and yellow fever.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Bacteriology: donovanosis?

Make a one-line identity card for each organism: shape and stain, defining test, toxin, disease and drug. Then use the flashcards and the other Microbiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.