Communicable diseases: fractional IPV in the immunisation schedule: practice question

A PSM question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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PSM · Communicable diseases: fractional IPV in the immunisation schedule

Sample item

In India's universal immunisation schedule, what are the route and dose of fractional inactivated polio vaccine?

AIntradermal, 0.5 mLBSubcutaneous, 0.5 mLCIntradermal, 0.1 mLDIntramuscular, 0.5 mL

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Intradermal, 0.1 mL

Fractional IPV is one-fifth of the full dose, 0.1 mL given intradermally, at 6 and 14 weeks. It saves vaccine and gives comparable seroconversion. The full intramuscular dose is 0.5 mL.

Option by option

A. Intradermal, 0.5 mL
Intradermal 0.5 mL is impossible volume for intradermal injection and not the schedule.
B. Subcutaneous, 0.5 mL
Subcutaneous 0.5 mL is a full-dose route that is not used for fIPV in the programme.
C. Intradermal, 0.1 mL (correct)
Correct. fIPV is 0.1 mL by the intradermal route.
D. Intramuscular, 0.5 mL
Intramuscular 0.5 mL is the full dose of IPV and not the fractional dose.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this PSM question

What is the answer to this PSM question?

The best answer is C, Intradermal, 0.1 mL. Fractional IPV is one-fifth of the full dose, 0.

Why is "Intradermal, 0.5 mL" not the answer?

Intradermal 0.5 mL is impossible volume for intradermal injection and not the schedule.

Why is "Subcutaneous, 0.5 mL" not the answer?

Subcutaneous 0.5 mL is a full-dose route that is not used for fIPV in the programme.

Why is "Intramuscular, 0.5 mL" not the answer?

Intramuscular 0.5 mL is the full dose of IPV and not the fractional dose.

What concept does this question test?

It tests Communicable diseases: fractional IPV in the immunisation schedule in PSM. 1 mL given intradermally, at 6 and 14 weeks. It saves vaccine and gives comparable seroconversion. The full intramuscular dose is 0.5 mL.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Communicable diseases: fractional IPV in the immunisation schedule?

Practise biostatistics with small calculations until sensitivity, predictive values and risk measures are automatic. Then use the flashcards and the other PSM questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.