Oral and maxillofacial surgery and facial fractures: von Willebrand disease: practice question

A Dentistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dentistry · Oral and maxillofacial surgery and facial fractures: von Willebrand disease

Sample item

A 12-year-old with easy bruising and prolonged bleeding from minor cuts needs a molar extraction. Platelet count is normal, aPTT is slightly prolonged and ristocetin cofactor activity is reduced. Which prophylaxis suits mild disease?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Desmopressin with tranexamic acid

Mild von Willebrand disease responds to desmopressin, which releases stored von Willebrand factor. Tranexamic acid protects the clot in the mouth.

Option by option

  • A. Vitamin K

    Vitamin K corrects clotting factor deficiency from vitamin K lack, not this disorder.

  • B. Platelet transfusion

    Platelet numbers are normal and a transfusion does not correct the factor.

  • C. Fresh frozen plasma

    Plasma is not needed for mild disease and carries infection risk.

  • D. Desmopressin with tranexamic acid (correct)

    Correct. Desmopressin and an antifibrinolytic cover a dental extraction in mild disease.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dentistry question

What is the answer to this Dentistry question?

The best answer is D, Desmopressin with tranexamic acid. Mild von Willebrand disease responds to desmopressin, which releases stored von Willebrand factor.

Why is "Vitamin K" not the answer?

Vitamin K corrects clotting factor deficiency from vitamin K lack, not this disorder.

Why is "Platelet transfusion" not the answer?

Platelet numbers are normal and a transfusion does not correct the factor.

Why is "Fresh frozen plasma" not the answer?

Plasma is not needed for mild disease and carries infection risk.

What concept does this question test?

It tests Oral and maxillofacial surgery and facial fractures: von Willebrand disease in Dentistry. Tranexamic acid protects the clot in the mouth.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Oral and maxillofacial surgery and facial fractures: von Willebrand disease?

Learn the dental formula, eruption ages and tooth structure once, as tables. Then use the flashcards and the other Dentistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.