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Forensic Medicine · Injuries and wounds: acute radiation syndrome
Sample itemAfter a radiation accident, which simple blood test in the first 24 to 48 hours best predicts the severity of exposure?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Absolute lymphocyte count
Lymphocytes are the most radiosensitive circulating cells, so a rapid fall in the absolute lymphocyte count within the first two days indicates a higher dose. Platelet and haemoglobin changes appear later, and creatinine reflects kidney function.
Option by option
A. Haemoglobin concentration
Haemoglobin changes slowly because red cells live for months.
B. Serum creatinine
Creatinine reflects renal function and not early radiation dose.
C. Platelet count
Platelets fall later as bone marrow stem cells are depleted.
D. Absolute lymphocyte count (correct)
Correct. The early fall in lymphocytes is the best early guide to dose.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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