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Forensic Medicine · Medical law and ethics: clinical equipoise
Sample itemA trial randomises patients between two treatments only when the medical community is genuinely uncertain which is better. Which concept justifies this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Clinical equipoise
Clinical equipoise means genuine uncertainty among experts about the comparative merits of the interventions, which makes randomisation ethical. Therapeutic misconception is a participant's wrongly believing the trial is for personal benefit.
Option by option
A. Informed refusal
Informed refusal is the patient's right to decline and does not justify randomisation.
B. Therapeutic misconception
Therapeutic misconception is a participant's error, not a justification of randomisation.
C. Distributive justice
Distributive justice concerns fair allocation of burdens and benefits.
D. Clinical equipoise (correct)
Correct. Genuine uncertainty among experts justifies randomisation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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