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General Surgery · Hepatobiliary and pancreatic surgery: albumin with large-volume paracentesis
Sample itemA man with cirrhosis and tense ascites undergoes removal of 8 litres of ascitic fluid in one session. Which measure best prevents post-paracentesis circulatory dysfunction and renal impairment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Intravenous albumin infusion after the procedure
Removal of a large volume of ascites triggers effective hypovolaemia and renin-angiotensin activation. Albumin infusion expands the plasma volume and reduces circulatory dysfunction and hepatorenal injury.
Option by option
A. Normal saline bolus alone
Saline alone does not stay in the vascular space as albumin does.
B. Intravenous furosemide bolus
A diuretic bolus would deplete volume further.
C. Intravenous albumin infusion after the procedure (correct)
Correct. Albumin is given when large volumes are removed.
D. Fluid restriction to 500 mL a day
Fluid restriction would worsen effective hypovolaemia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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