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Microbiology · Bacteriology: ecthyma gangrenosum
Sample itemA neutropenic patient on chemotherapy develops painless dark necrotic skin lesions with a surrounding erythematous rim. Blood cultures grow an oxidase-positive Gram-negative bacillus. What is the likely organism?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Pseudomonas aeruginosa
Ecthyma gangrenosum is a vasculitic skin lesion from Pseudomonas bacteraemia in neutropenic hosts. E. coli is oxidase negative, group A streptococcus is a Gram-positive coccus, and Acinetobacter is oxidase negative.
Option by option
A. Acinetobacter baumannii
Acinetobacter is oxidase negative.
B. Streptococcus pyogenes
S. pyogenes is a Gram-positive coccus.
C. Escherichia coli
E. coli is oxidase negative and does not typically cause this lesion.
D. Pseudomonas aeruginosa (correct)
Correct. Ecthyma gangrenosum with an oxidase-positive bacillus points to Pseudomonas.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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