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Physiology · Respiratory system: emphysema mechanics
Sample itemA 62-year-old smoker has a barrel chest, prolonged expiration and a very low FEV1/FVC. Why do his small airways collapse during forced expiration?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Loss of elastic recoil reduces radial traction on the airways
Destruction of alveolar walls removes the radial traction that holds small airways open, so they collapse early in expiration and air trapping results. Compliance and total lung capacity are increased.
Option by option
A. Fibrosis of the alveolar septa
Fibrosis stiffens the lung and is the pattern of restrictive disease.
B. Excessive surfactant raising surface tension
Surfactant lowers surface tension, and excess would not collapse airways.
C. Hypertrophy of bronchial smooth muscle
Smooth muscle hypertrophy is the feature of asthma, not emphysema.
D. Loss of elastic recoil reduces radial traction on the airways (correct)
Correct. Loss of elastic tissue removes radial traction and airways collapse.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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