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PSM · Communicable diseases: congenital rubella syndrome
Sample itemAn infant has cataract, patent ductus arteriosus and sensorineural deafness. The mother had a mild rash with fever in her first trimester. Which is the cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Congenital rubella infection
Cataract, patent ductus arteriosus and sensorineural deafness are the classic triad of congenital rubella syndrome after maternal infection in early pregnancy. Rubella vaccination of girls and women, as in measles-rubella vaccine, aims to prevent it.
Option by option
A. Congenital rubella infection (correct)
Correct. This triad is typical of congenital rubella.
B. Neonatal herpes
Neonatal herpes causes vesicles and encephalitis in the newborn.
C. Congenital syphilis
Congenital syphilis gives snuffles, rash and bone changes.
D. Congenital toxoplasmosis
Toxoplasmosis gives chorioretinitis, hydrocephalus and intracranial calcification.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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