Obstetric immunology: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Obstetric immunology

Sample item

An Rh-negative mother delivers an Rh-positive baby. When should anti-D immunoglobulin be given?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Within 72 hours of delivery

Anti-D should be given as soon as possible, and within 72 hours, to prevent sensitisation. It is also given at around 28 weeks and after events such as miscarriage, amniocentesis or abdominal trauma, depending on local protocol.

Option by option

  • A. Within 72 hours of delivery (correct)

    Correct.

  • B. Within 7 days of delivery

    Delaying to 7 days leaves a gap where sensitisation can occur.

  • C. It is not needed

    Without it the mother can become sensitised and affect future pregnancies.

  • D. Within one month of delivery

    A month is too late to be effective.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this OBG question

What is the answer to this OBG question?

The best answer is A, Within 72 hours of delivery. Anti-D should be given as soon as possible, and within 72 hours, to prevent sensitisation.

Why is "Within 7 days of delivery" not the answer?

Delaying to 7 days leaves a gap where sensitisation can occur.

Why is "It is not needed" not the answer?

Without it the mother can become sensitised and affect future pregnancies.

Why is "Within one month of delivery" not the answer?

A month is too late to be effective.

What concept does this question test?

It tests Obstetric immunology in OBG. It is also given at around 28 weeks and after events such as miscarriage, amniocentesis or abdominal trauma, depending on local protocol.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Obstetric immunology?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.