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Ophthalmology · Glaucoma
Sample itemWhich drug is given systemically to reduce intraocular pressure in acute angle-closure glaucoma?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Intravenous acetazolamide
Acute angle-closure presents with a painful red eye, a mid-dilated fixed pupil, corneal oedema and halos. Treatment lowers pressure with acetazolamide, topical beta-blockers, pilocarpine and osmotic agents, followed by laser iridotomy. Mydriatics such as atropine worsen angle closure.
Option by option
A. Cyclopentolate eye drops
Cyclopentolate is also a mydriatic and is harmful here.
B. Intravenous acetazolamide (correct)
Correct. It reduces aqueous humour production.
C. Atropine eye drops
Atropine dilates the pupil and can precipitate or worsen angle closure.
D. Phenylephrine eye drops
Phenylephrine dilates the pupil and is avoided.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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