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Ophthalmology · Retina
Sample itemA 16-year-old boy has poor vision in dim light since childhood and gradually narrowing visual fields. Fundus shows bone-spicule pigmentation in the mid-periphery, attenuated retinal arterioles and a waxy pale disc. Which investigation best demonstrates the functional defect?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Electroretinogram
This is retinitis pigmentosa, a rod-cone dystrophy in which rods are lost first, causing night blindness and ring scotomas. The electroretinogram is markedly reduced or extinguished early, often before fundus changes are obvious.
Option by option
A. Visual evoked potential
VEP tests the visual pathway and does not specifically show the photoreceptor defect.
B. Amsler grid testing
The Amsler grid detects central distortion in macular disease rather than diffuse photoreceptor dysfunction.
C. Electroretinogram (correct)
It records the retinal photoreceptor response and shows the early, marked loss in rod-cone dystrophy.
D. B-scan ultrasonography
B-scan shows structural lesions behind opaque media, not photoreceptor function.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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