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Ophthalmology · Neuro-ophthalmology
Sample itemA 60-year-old woman has a sudden severe headache followed by drooping of the right upper lid. The right eye is deviated down and out and the pupil is dilated and non-reactive. What is the most important cause to exclude urgently?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Posterior communicating artery aneurysm
A complete oculomotor palsy with pupil involvement suggests compression of the nerve, since pupillary fibres lie superficially. A posterior communicating artery aneurysm is the classic cause and risks subarachnoid haemorrhage, so urgent vascular imaging is needed.
Option by option
A. Posterior communicating artery aneurysm (correct)
Compression by an aneurysm affects the superficial pupillary fibres and may rupture, so it must be excluded promptly.
B. Diabetic microvascular ischaemia of the nerve
Diabetic ischaemia typically spares the pupil and is a lower-risk diagnosis.
C. Horner syndrome
Horner syndrome causes a small pupil and mild ptosis, not a dilated pupil with eye deviation.
D. Myasthenia gravis
Myasthenia does not affect the pupil and varies through the day.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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