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Pediatrics · Neonatology
Sample itemA newborn becomes visibly jaundiced in the first 24 hours of life. What is the most likely cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Haemolytic disease of the newborn
Jaundice within 24 hours is never physiological. Think haemolysis first: ABO or Rh incompatibility, or G6PD deficiency. Physiological jaundice appears after 24 hours, peaks at day 3–5 and fades.
Option by option
A. Biliary atresia
Biliary atresia causes conjugated jaundice that appears later and persists.
B. Breast-milk jaundice
Breast-milk jaundice appears in the second week.
C. Haemolytic disease of the newborn (correct)
Correct.
D. Physiological jaundice
Physiological jaundice starts after 24 hours.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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