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Pharmacology · Emergency drugs
Sample itemA patient develops stridor, wheeze and hypotension minutes after an injection. What is the first-line drug and route?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Intramuscular adrenaline
Anaphylaxis is treated first with intramuscular adrenaline in the anterolateral thigh. Antihistamines and steroids are only adjuncts and do not reverse airway obstruction or shock.
Option by option
A. Oral chlorpheniramine
Oral drugs are far too slow and unreliable in shock.
B. Intramuscular adrenaline (correct)
Correct. Give it early; it can be repeated.
C. Intravenous hydrocortisone
Steroids act slowly and do not treat the emergency.
D. Nebulised salbutamol
Salbutamol helps bronchospasm but not hypotension or airway oedema.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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