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Anaesthesia · Respiratory physiology and ventilation: curriculum recognition
Sample itemIn a paralysed patient on controlled ventilation with constant CO2 production, the volume of fresh gas reaching perfused alveoli each minute is doubled. What happens to the arterial PaCO2?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Falls to about half
PaCO2 is directly proportional to CO2 production and inversely proportional to alveolar ventilation. Doubling the effective ventilation therefore halves the PaCO2 when production is constant. Oxygenation is much less sensitive to the same change.
Option by option
A. Rises slightly
A rise would occur with reduced ventilation, not increased ventilation.
B. Doubles
Doubling would follow halving the ventilation, not doubling it.
C. Remains unchanged
PaCO2 changes whenever alveolar ventilation changes at constant production.
D. Falls to about half (correct)
Correct. PaCO2 varies inversely with alveolar ventilation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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