Cardiovascular physiology, fluids, and blood management: curriculum recognition: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Cardiovascular physiology, fluids, and blood management: curriculum recognition

Sample item

A woman with postpartum haemorrhage has lost 3 L of blood, and the fibrinogen is 0.8 g/L despite red cells and plasma. Which product is the most concentrated source of fibrinogen?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Cryoprecipitate

Cryoprecipitate is rich in fibrinogen, factor VIII, von Willebrand factor and factor XIII, and a small volume raises the fibrinogen substantially. Fresh frozen plasma contains fibrinogen at a much lower concentration, so large volumes would be needed.

Option by option

  • A. Fresh frozen plasma

    Plasma contains fibrinogen only at physiological concentration and would need a large volume.

  • B. Platelet concentrate

    Platelets do not supply a meaningful amount of fibrinogen.

  • C. Cryoprecipitate (correct)

    Correct. Cryoprecipitate concentrates fibrinogen in a small volume.

  • D. Packed red cells

    Red cells contain no clotting factors.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is C, Cryoprecipitate. Cryoprecipitate is rich in fibrinogen, factor VIII, von Willebrand factor and factor XIII, and a small volume raises the fibrinogen substantially.

Why is "Fresh frozen plasma" not the answer?

Plasma contains fibrinogen only at physiological concentration and would need a large volume.

Why is "Platelet concentrate" not the answer?

Platelets do not supply a meaningful amount of fibrinogen.

Why is "Packed red cells" not the answer?

Red cells contain no clotting factors.

What concept does this question test?

It tests Cardiovascular physiology, fluids, and blood management: curriculum recognition in Anaesthesia. Fresh frozen plasma contains fibrinogen at a much lower concentration, so large volumes would be needed.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Cardiovascular physiology, fluids, and blood management: curriculum recognition?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.