Vesiculobullous disorders mnemonic

Direct immunofluorescence patterns

The mnemonic

Fish net, Line, Grain

What each word stands for

  • Fish netPemphigus: intercellular IgG
  • LineBullous pemphigoid: linear IgG and C3 at basement membrane
  • GrainDermatitis herpetiformis: granular IgA in dermal papillae

Why it matters clinically

A common exam question that links the pattern to the disease.

Where it stops being reliable

Linear IgA disease also shows a linear pattern, but with IgA.

Teaching aid, still awaiting independent review. Confirm facts in a standard source.

More mnemonics

Common questions

What is the Vesiculobullous disorders mnemonic?

Fish net, Line, Grain. It helps you recall: Direct immunofluorescence patterns.

What does "Fish net" stand for?

Pemphigus: intercellular IgG

What does "Line" stand for?

Bullous pemphigoid: linear IgG and C3 at basement membrane

What does "Grain" stand for?

Dermatitis herpetiformis: granular IgA in dermal papillae

What are all the parts of the Fish net, Line, Grain mnemonic?

Fish net: Pemphigus: intercellular IgG; Line: Bullous pemphigoid: linear IgG and C3 at basement membrane; Grain: Dermatitis herpetiformis: granular IgA in dermal papillae.

Which topic does this mnemonic belong to?

It belongs to Vesiculobullous disorders in Dermatology.

Where does this mnemonic stop being reliable?

Linear IgA disease also shows a linear pattern, but with IgA.

How is this useful clinically?

A common exam question that links the pattern to the disease.

How do I make this mnemonic stick?

Say it aloud, write it from memory tomorrow, then again in a week. Then test yourself on a Dermatology question about Vesiculobullous disorders.

Is this a standard mnemonic?

It is a teaching aid written or adapted by our team. Some resemble ones students share informally. Check any fact that matters in a standard source.