The mnemonic
ABCDE
What each word stands for
- AAsymmetry
- BBorder irregularity
- CColour variation
- DDiameter more than 6 mm
- EEvolving, changing over time
Why it matters clinically
Used for screening pigmented lesions.
Where it stops being reliable
Nodular melanoma may be symmetrical and small; the rule is not diagnostic.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.