The mnemonic
SOAP BRAIN MD
What each word stands for
- SSerositis
- OOral ulcers
- AArthritis
- PPhotosensitivity
- BBlood disorders
- RRenal disease
- AAntinuclear antibody
- IImmunological abnormalities (anti-dsDNA, anti-Smith)
- NNeurological disorder (seizures, psychosis)
- MMalar rash
- DDiscoid rash
Why it matters clinically
Four or more of the eleven criteria classify a patient as having SLE.
Where it stops being reliable
Newer EULAR/ACR 2019 criteria require ANA positivity and use weighted scoring.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.