The mnemonic
Porosis normal, Malacia low, Paget ALP high
What each word stands for
- Porosis normalOsteoporosis: calcium, phosphate and ALP normal
- Malacia lowOsteomalacia and rickets: low vitamin D with raised ALP, often low calcium or phosphate
- Paget ALP highPaget disease: markedly raised ALP with normal calcium and phosphate
Why it matters clinically
Helps interpret a typical biochemistry panel in a patient with bone pain.
Where it stops being reliable
Simplified; hyperparathyroidism and renal bone disease have their own patterns.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.