The mnemonic
FEVER
What each word stands for
- FFever
- EEncephalopathy
- VVitals unstable (autonomic instability)
- EElevated creatine kinase
- RRigidity (lead-pipe)
Why it matters clinically
Stop the antipsychotic; give supportive care, with dantrolene or bromocriptine in severe cases.
Where it stops being reliable
Does not separate NMS from serotonin syndrome; look for clonus and onset speed.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.