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Anaesthesia · Monitoring
Sample itemA patient rescued from a house fire is breathless and has a headache, but pulse oximetry reads 99% on room air. Why is the reading unreliable?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Carboxyhaemoglobin is read as oxyhaemoglobin, so SpO2 is falsely normal
Standard two-wavelength pulse oximeters cannot distinguish carboxyhaemoglobin from oxyhaemoglobin, since both absorb red light similarly. SpO2 therefore overestimates true oxygen saturation in carbon monoxide poisoning. Co-oximetry on an arterial blood gas sample gives the true value.
Option by option
A. Pulse oximeters detect only plasma dissolved oxygen
Pulse oximeters measure haemoglobin saturation, not dissolved oxygen.
B. Carboxyhaemoglobin is read as oxyhaemoglobin, so SpO2 is falsely normal (correct)
Correct. The device misreads carboxyhaemoglobin as oxygenated haemoglobin.
C. Carboxyhaemoglobin is read as deoxyhaemoglobin, so SpO2 is falsely low
Carboxyhaemoglobin does not read as deoxyhaemoglobin, so the error is a falsely high, not low, value.
D. Skin pigmentation always reduces readings by half
Skin pigmentation can cause small inaccuracies, not a halving of the value.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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