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Anaesthesia · Monitoring
Sample itemDuring a laparoscopic cholecystectomy, there is an abrupt fall in end-tidal CO2 from 38 to 10 mmHg with hypotension, tachycardia and a mill-wheel murmur. What is the most likely cause and the next immediate step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Venous gas embolism; stop insufflation, release pneumoperitoneum and place the patient head-down on the left side
A sudden fall in ETCO2 with hypotension and a mill-wheel murmur indicates a gas embolus, which increases dead space and obstructs the right ventricular outflow. Insufflation is stopped, the pneumoperitoneum released, 100% oxygen given and the patient placed left lateral head-down (Durant position). Aspiration through a central line may be attempted.
Option by option
A. Venous gas embolism; stop insufflation, release pneumoperitoneum and place the patient head-down on the left side (correct)
Correct. Sudden ETCO2 fall plus hypotension and a mill-wheel murmur point to gas embolism.
B. Tension pneumothorax; perform needle decompression only
Tension pneumothorax raises airway pressure and a mill-wheel murmur is not a feature of it.
C. Malignant hyperthermia; give dantrolene
Malignant hyperthermia causes a rise in ETCO2, not a fall.
D. Oesophageal intubation; remove the tube
Oesophageal intubation would give no CO2 trace from the start, not an abrupt fall mid-procedure.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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