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Pharmacology · Autonomic: isoprenaline
Sample itemA patient with complete heart block and recurrent torsades de pointes secondary to bradycardia needs temporary rate support until a pacemaker is available. Which drug is suitable?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Isoprenaline infusion
Isoprenaline, a non-selective beta agonist, increases heart rate and conduction and shortens the QT interval by raising the rate, which suppresses pause-dependent torsades. It is a bridge until pacing.
Option by option
A. Verapamil
Verapamil slows AV conduction and would worsen block.
B. Phenylephrine
Phenylephrine causes reflex bradycardia through vasoconstriction.
C. Isoprenaline infusion (correct)
Correct. Beta stimulation increases rate and suppresses pause-dependent torsades.
D. Propranolol
Propranolol would worsen bradycardia and heart block.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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