Antimicrobials: clarithromycin in H. pylori and MAC: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Antimicrobials: clarithromycin in H. pylori and MAC

Sample item

Clarithromycin is a component of which two regimens?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Helicobacter pylori eradication and Mycobacterium avium complex treatment

Clarithromycin is part of triple therapy for H. pylori with a PPI and amoxicillin, and is used in MAC infection in combination with ethambutol and rifampicin or rifabutin. It inhibits CYP3A4.

Option by option

  • A. Pneumocystis prophylaxis and malaria treatment

    Pneumocystis uses cotrimoxazole, and malaria uses antimalarials.

  • B. Helicobacter pylori eradication and Mycobacterium avium complex treatment (correct)

    Correct. These are the standard uses.

  • C. Scabies and pediculosis

    Scabies uses permethrin or ivermectin.

  • D. Treatment of syphilis and typhoid

    Syphilis uses penicillin and typhoid uses azithromycin or ceftriaxone.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is B, Helicobacter pylori eradication and Mycobacterium avium complex treatment. Clarithromycin is part of triple therapy for H.

Why is "Pneumocystis prophylaxis and malaria treatment" not the answer?

Pneumocystis uses cotrimoxazole, and malaria uses antimalarials.

Why is "Scabies and pediculosis" not the answer?

Scabies uses permethrin or ivermectin.

Why is "Treatment of syphilis and typhoid" not the answer?

Syphilis uses penicillin and typhoid uses azithromycin or ceftriaxone.

What concept does this question test?

It tests Antimicrobials: clarithromycin in H. pylori and MAC in Pharmacology. pylori with a PPI and amoxicillin, and is used in MAC infection in combination with ethambutol and rifampicin or rifabutin. It inhibits CYP3A4.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Antimicrobials: clarithromycin in H. pylori and MAC?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.