Urology: prostate cancer diagnosis: practice question

A General Surgery question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

General Surgery · Urology: prostate cancer diagnosis

Sample item

A 66-year-old has a PSA of 14 ng/mL. What is the best next step to diagnose prostate cancer?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Multiparametric MRI followed by targeted biopsy

MRI before biopsy identifies clinically significant lesions and allows targeted sampling in addition to systematic cores, and the Gleason or ISUP grade then guides treatment. Treatment without histology is not appropriate.

Option by option

  • A. Radical prostatectomy without tissue diagnosis

    Surgery needs histology first.

  • B. Multiparametric MRI followed by targeted biopsy (correct)

    Correct. MRI-guided biopsy is the modern pathway.

  • C. Repeat PSA in 1 year

    Waiting a year is unsafe with this PSA.

  • D. Immediate androgen deprivation

    ADT needs tissue diagnosis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More General Surgery questions

Questions about this General Surgery question

What is the answer to this General Surgery question?

The best answer is B, Multiparametric MRI followed by targeted biopsy. MRI before biopsy identifies clinically significant lesions and allows targeted sampling in addition to systematic cores, and the Gleason or ISUP grade then guides treatment.

Why is "Radical prostatectomy without tissue diagnosis" not the answer?

Surgery needs histology first.

Why is "Repeat PSA in 1 year" not the answer?

Waiting a year is unsafe with this PSA.

Why is "Immediate androgen deprivation" not the answer?

ADT needs tissue diagnosis.

What concept does this question test?

It tests Urology: prostate cancer diagnosis in General Surgery. Treatment without histology is not appropriate.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Urology: prostate cancer diagnosis?

Learn classic signs and eponyms alongside what they diagnose. Then use the flashcards and the other General Surgery questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.