Chemotherapy: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Chemotherapy

Sample item

Methotrexate inhibits what enzyme?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Dihydrofolate reductase

This item reviews Chemotherapy; Dihydrofolate reductase is the best answer because it directly matches the drug or organism pattern described.

Option by option

  • A. Xanthine oxidase

    Xanthine oxidase does not fit the stated mechanism or pattern.

  • B. COX

    COX is plausible but is not the best answer here.

  • C. Na-K ATPase

    Na-K ATPase is not supported by the key finding.

  • D. Dihydrofolate reductase (correct)

    Correct. Dihydrofolate reductase is supported by the defining feature.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is D, Dihydrofolate reductase. This item reviews Chemotherapy; Dihydrofolate reductase is the best answer because it directly matches the drug or organism pattern described.

Why is "Xanthine oxidase" not the answer?

Xanthine oxidase does not fit the stated mechanism or pattern.

Why is "COX" not the answer?

COX is plausible but is not the best answer here.

Why is "Na-K ATPase" not the answer?

Na-K ATPase is not supported by the key finding.

What concept does this question test?

It tests Chemotherapy in Pharmacology. The correct option holds because: Correct. Dihydrofolate reductase is supported by the defining feature.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Chemotherapy?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.