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Anaesthesia · Critical care: septic shock vasopressor target
Sample itemIn septic shock, what initial mean arterial pressure target is recommended with norepinephrine?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. 65 mmHg
Surviving Sepsis guidelines recommend an initial target mean arterial pressure of 65 mmHg using norepinephrine as the first-line vasopressor. Higher targets did not improve outcome and increased arrhythmias. Individual targets may be adjusted in chronic hypertension.
Option by option
A. 90 mmHg
Higher targets of 90 mmHg were not beneficial.
B. 65 mmHg (correct)
Correct. A MAP of 65 mmHg is the recommended starting target.
C. 45 mmHg
A MAP of 45 mmHg is inadequate for organ perfusion.
D. 110 mmHg
A MAP of 110 mmHg is excessive and harmful.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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