Critical care: initial fluid in sepsis-induced hypoperfusion: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Critical care: initial fluid in sepsis-induced hypoperfusion

Sample item

For sepsis-induced hypoperfusion or septic shock, what initial crystalloid volume do guidelines suggest within the first 3 hours?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. At least 30 mL/kg

The Surviving Sepsis Campaign suggests at least 30 mL/kg of intravenous crystalloid within the first 3 hours, followed by reassessment of fluid responsiveness. Balanced crystalloids are preferred over saline. Further fluids are guided by dynamic measures such as capillary refill, lactate and passive leg raising.

Option by option

  • A. 100 mL/kg

    100 mL/kg risks overload and is not recommended.

  • B. Colloids only, 10 mL/kg

    Crystalloids, not colloids, are first choice.

  • C. 5 mL/kg

    5 mL/kg is too little for resuscitation of shock.

  • D. At least 30 mL/kg (correct)

    Correct. 30 mL/kg of crystalloid is the suggested initial volume.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is D, At least 30 mL/kg. The Surviving Sepsis Campaign suggests at least 30 mL/kg of intravenous crystalloid within the first 3 hours, followed by reassessment of fluid responsiveness.

Why is "100 mL/kg" not the answer?

100 mL/kg risks overload and is not recommended.

Why is "Colloids only, 10 mL/kg" not the answer?

Crystalloids, not colloids, are first choice.

Why is "5 mL/kg" not the answer?

5 mL/kg is too little for resuscitation of shock.

What concept does this question test?

It tests Critical care: initial fluid in sepsis-induced hypoperfusion in Anaesthesia. Balanced crystalloids are preferred over saline. Further fluids are guided by dynamic measures such as capillary refill, lactate and passive leg raising.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Critical care: initial fluid in sepsis-induced hypoperfusion?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.