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Anatomy · Embryology: fertilisation and implantation
Sample itemA woman with scarring from previous pelvic inflammatory disease is counselled about her risk of ectopic pregnancy. Where does fertilisation normally occur, and when does implantation of the blastocyst begin?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. In the ampulla of the uterine tube, with implantation beginning about 6 to 7 days after fertilisation
Fertilisation normally takes place in the ampulla of the uterine tube. The zygote cleaves while travelling to the uterus and the blastocyst starts implanting in the endometrium around day 6 to 7. Damage to tubal cilia or the lumen delays transport and raises the risk of implantation in the tube.
Option by option
A. In the ampulla of the uterine tube, with implantation beginning about 6 to 7 days after fertilisation (correct)
Correct. The ampulla is the usual site, and implantation begins at about day 6 to 7.
B. In the uterine cavity, with implantation beginning at 14 days after fertilisation
Fertilisation does not take place in the uterine cavity, and implantation begins earlier than day 14.
C. In the isthmus of the uterine tube, with implantation beginning about 2 days after fertilisation
The isthmus is not the usual site of fertilisation, and implantation at day 2 is far too early.
D. In the infundibulum, with implantation completed on the third day
The infundibulum is the funnel-shaped opening, and implantation is not complete at day 3.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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